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Peptidomics: Identification and Quantification of Endogenous Peptides in Neuroendocrine Tissues

✍ Scribed by Lloyd D. Fricker; Jihyeon Lim; Hui Pan; Fa-Yun Che


Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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Peptidomics: Identification and quantifi
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## Abstract Neuropeptides perform a large variety of functions as intercellular signaling molecules. While most proteomic studies involve digestion of the proteins with trypsin or other proteases, peptidomics studies usually analyze the native peptide forms. Neuropeptides can be studied by using ma

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## Abstract Recent work on protein and peptide biomarker patterns revealed the difficulties in identifying their molecular components, which is indispensable for validation of the biological context. Cerebrospinal fluid and brain tissue are used as sources to discover new biomarkers, e.g. for neuro