## Abstract Mucus hypersecretion is an important characteristic feature of the pathogenesis of allergy. Although interleukin (IL)‐4 is known to be an inflammatory mediator in respiratory diseases, the mechanism by which IL‐4 induces __MUC5AC__ gene expression has not been fully explored. The aim of
✦ LIBER ✦
Peptidoglycan fromStaphylococcus aureusincreasesMUC5ACgene expressionviaRSK1-CREB pathway in human airway epithelial cells
✍ Scribed by Young Ok Kim; Min Jung Jung; Jang Kyu Choi; Do Whan Ahn; Kyoung Seob Song
- Publisher
- Korean Society for Molecular and Cellular Biology
- Year
- 2011
- Tongue
- English
- Weight
- 659 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1016-8478
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## Abstract We have shown that the tobacco nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) is an agonist for β‐adrenergic receptors (β‐ARs) and increased DNA synthesis of human lung adenocarinoma cells with features of bronchiolar Clara cells by binding to these receptors. Using a