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Peptide vaccines for hematological malignancies: a missed promise?

โœ Scribed by Bocchia, Monica; Defina, Marzia; Aprile, Lara; Sicuranza, Anna


Book ID
121555036
Publisher
Carden Jennings Publishing
Year
2014
Tongue
English
Weight
374 KB
Volume
99
Category
Article
ISSN
0925-5710

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## Abstract The doubleโ€stranded RNAโ€dependent kinase PKR has been described for many years as strictly a proโ€apoptotic kinase. Recent data suggest that the main purpose of this kinase is damage control and repair following stress and, if all else fails, apoptosis. Aberrant activation of PKR has bee