✦ LIBER ✦
Peptide-unit assembling via disulfide cross-linking: A versatile approach which enables the creation of artificial proteins comprising helices with different amino acid sequences
✍ Scribed by Shiroh Futaki; Kouki Kitagawa
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 718 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
✦ Synopsis
Al/~a'a~:. A versatile approach was developed to create artificial proteins by assembling cthelical peptide unit via selective disulfide cross-linking, which feature should open a way to the construction of the artificial functional proteins having arbitrary combination, arrangement, and orientation of helices. The practicability of this approach was demonstrated through the synthesis of a four-helix-bundle protein composed of 84 amino acid residues.