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Peptide transporter 2 (PEPT2) expression in brain protects against 5-aminolevulinic acid neurotoxicity

โœ Scribed by Yongjun Hu; Hong Shen; Richard F. Keep; David E. Smith


Book ID
111180443
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
192 KB
Volume
103
Category
Article
ISSN
0022-3042

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We describe the synthesis of a fluorescent dipeptide derivative, โค-Ala-Lys-N -AMCA, which could be used as an excellent reporter molecule for studying the oligopeptide transport system in brain cell cultures. Fluorescence microscopic and immunocytochemical studies revealed that the reporter peptide