Peptide Structure Stabilization: A Study Of Aromatic-aromatic Interaction And pH Effect On A β-hairpin Stability
✍ Scribed by Wu, Ling; Takekiyo, Takahiro; McElheny, Dan; Keiderling, Timothy A.
- Book ID
- 119204852
- Publisher
- Biophysical Society
- Year
- 2009
- Tongue
- English
- Weight
- 81 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0006-3495
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## Abstract The effects of N‐methylation and chain length on a cation–π interaction have been investigated within the context of a β‐hairpin peptide. Significant enhancement of the interaction and structural stabilization of the hairpin have been observed upon Lys methylation. Thermodynamic analysi
## Abstract Two different strategies have been employed for the synthesis of Fmoc‐protected β^3^‐homoarginine; the Arndt–Eistert homologation of α‐arginine and the guanidinylation of β^3^‐homoornithine. Solid‐phase β‐peptide synthesis was used for the preparation of β‐heptapeptide **1**, which was