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Peptide nucleic acids on microarrays and other biosensors

✍ Scribed by Ole Brandt; Jörg D. Hoheisel


Book ID
113931826
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
233 KB
Volume
22
Category
Article
ISSN
0167-7799

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## Abstract Peptide nucleic acids (PNAs) are DNA mimics with a neutral peptide backbone instead of the negatively charged sugar phosphates. PNAs exhibit several attractive features such as high chemical and thermal stability, resistance to enzymatic degradation, and stable binding to their RNA or D