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Peptide-Morpholino Conjugate: A Promising Therapeutic for Duchenne Muscular Dystrophy

✍ Scribed by Hong M. Moulton; Bo Wu; Natee Jearawiriyapaisarn; Peter Sazani; Qi Long Lu; Ryszard Kole


Book ID
111399375
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
268 KB
Volume
1175
Category
Article
ISSN
0890-6564

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## Abstract ## Background Antisense‐mediated exon skipping is a putative treatment for Duchenne muscular dystrophy (DMD). Using antisense oligonucleotides (AONs), the disrupted DMD reading frame is restored, allowing generation of partially functional dystrophin and conversion of a severe Duchenne