The syntheais, CD, ir spectroscopic, and conformational studies of a series of bridged cyclic peptides of the general formula, q&[NH-(CH,),-CO-Gly-Pro-Y-Gly] (2a-d, Y = Gly or Ser(OBu'), n = 4 or 2) is reported. As indicated by difference nuclear Overhauser enhancement and Fourier transform ir exper
Peptide models for β-turns.
✍ Scribed by Crisma, M. ;Fasman, G.D. ;Balaram, H. ;Balaram, P.
- Book ID
- 115098185
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 559 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0367-8377
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Reverse turns are a major class of protein secondary structure; they represent sites of chain reversal and thus sites where the globular character of a protein is created. It has been speculated for many years that turns may nucleate the formation of structure in protein folding, as the
## Abstract The conformational behavior of POE‐bound model peptides Boc‐(L‐Ala)~2~‐X‐Y‐(L‐Ala)~2~‐NHPOE (X – Y = L‐Pro‐Gly (**I**), Gly‐L‐Ile (**II**); NHPOE = aminopoly(oxyethylene)) as well as of the repetitive hexapeptide of elastin, Boc‐L‐Val‐L‐Ala‐L‐Pro‐Gly‐L‐Val‐Gly‐A‐NHPOE‐M (**III**) (A = p
This letter describes a scenario which provides for the stereospecific intro uction of both the amino and carboxyl termini portion of a designed B-turn mimetic. Peptides and proteins are ubiquitously distributed in nature, and play critical roles in the regulation of virtually all biological process
## Abstract In the present paper we describe the synthesis, purification, and single‐crystal x‐ray analysis of the cyclic tetrapeptide __cyclo__‐(L‐Pro‐L‐Phe‐β‐Ala‐β‐Ala). This compound contains the β‐alanyl‐β‐alanine dipeptide as putative cyclization arm to force the remaining dipeptide‐L‐Pro‐L‐Ph
## Abstract In the present paper we describe the synthesis, purification, and single crystal x‐ray analysis of the cyclic pentapeptide __cyclo__‐(L‐Pro‐L‐Pro‐L‐Phe‐β‐Ala‐β‐Ala). The peptide was synthesized by classical solution methods and the cyclization of the free pentapeptide was accomplished i