Peptide Inhibitors of the Mitogen-Activated Protein Kinase Pathway: A Structure-Mimetic Peptide Corresponding to the Conserved Inter-DFG-APE Region in the Kinase Domain

A peptide fragment of ependymin neurotro

A peptide fragment of ependymin neurotrophic factor uses protein kinase C and the mitogen-activated protein kinase pathway to activate c-Jun N-terminal kinase and a functional AP-1 containing c-Jun and c-Fos proteins in mouse NB2a cells

✍ David S. Adams; Brendan Hasson; Anne Boyer-Boiteau; Adam El-Khishin; Victor E. S 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 376 KB 👁 1 views

## Abstract Ependymin (EPN) is a goldfish brain neurotrophic factor previously shown to function in a variety of cellular events related to long‐term memory formation and neuronal regeneration. CMX‐8933, an 8‐amino‐acid synthetic peptide fragment of EPN, was designed for aiding an investigation of