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Peptide Deformylase of Eukaryotic Protists: A Target for New Antiparasitic Agents?

โœ Scribed by T Meinnel


Book ID
114177461
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
170 KB
Volume
16
Category
Article
ISSN
0169-4758

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Carbonic anhydrase IX: A new druggable t
โœ Jean-Yves Winum; Marouan Rami; Andrea Scozzafava; Jean-Louis Montero; Claudiu Su ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 199 KB

## Abstract Carbonic anhydrases (CAs, EC 4.2.1.1) are a family of enzymes widespread in all life kingdoms. In mammals, isozyme CA IX is highly overexpressed in many cancer types being present in few normal tissues. Its expression is strongly induced by hypoxia present in many tumors, being regulate