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Peptide conformations - 49(1): Synthesis and structure-activity relationships of side chain modified peptides of cyclo(-d-Pro-Phe-Thr-Lys-Trp-Phe-)

โœ Scribed by KESSLER, H. ;HAUPT, A. ;SCHUDOK, M. ;ZIEGLER, K. ;FRIMMER, M.


Book ID
115098811
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
744 KB
Volume
32
Category
Article
ISSN
0367-8377

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Alanine containing analogues of cyclo(-d
โœ H. Kessler; G. Gemmecker; A. Haupt; M. Klein; K. Wagner; M. Will ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 903 KB

Six analogues of the cyclic hexapeptide cyclo(-D-Pro-Phe-Thr-Lys(Z)-Trp-Phe-) (1) were synthesized in which each amino acid was substituted by an alanine or Dalanine residue, respectively. Their conformation was determined by two-dimensional NMR-spectroscopy and refined by restraint molecular dynami