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Peptide conformations. 33. Conformational analysis of cyclic enkephalin analogs of the type Tyr-cyclo-(-N ω -Xxx-Gly-Phe-Leu-)*

✍ Scribed by KESSLER, HORST ;HÖLZEMANN, GÜNTER ;ZECHEL, CHRISTIAN

Book ID
115098302
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
671 KB
Volume
25
Category
Article
ISSN
0367-8377

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A conformational study of the cyclic P-casomorphin-5 analogues H-Tyr-cyclo[ -D-Om-2-Nal-Pro-Gly-J (1) (p-selective agonist; 2-Nal = 2-naphthylalanine), H-Tyr-cyclo[-D-Orn-2-Nal-D-Pro- Gly-] (2) (mixed f.~ agonistl6 antagonist) and H-Tyr-cyclo[ -D-Om-Phe-D-Pro-Gly-] (3) (highly potent p and 6 agonis