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Peptide-Biphenyl Hybrids as Calpain Inhibitors

✍ Scribed by Ana Montero; Enrique Mann; Antonio Chana; Bernardo Herradón

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
263 KB
Volume
1
Category
Article
ISSN
1612-1872

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Synthesis of a 24-Membered Cyclic Peptid
Synthesis of a 24-Membered Cyclic Peptide-Biphenyl Hybrid
✍ Ana Montero; Fernando Albericio; Miriam Royo; Bernardo Herradón 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB

## Abstract The synthesis of a 24‐membered macrocyclic peptide‐biphenyl hybrid with four amino acid residues and two biphenyl fragments was performed by a combination of solid‐phase and solution methodologies. The acyclic precursor was prepared by a solid phase methodology whereas the final macrocy