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Peptide based cytotoxic T-cell vaccines; delivery of multiple epitopes, help, memory and problems

✍ Scribed by Suzanne L Elliott; Stephanie Pye; Thuy Le; Luis Mateo; John Cox; Lisa Macdonald; Anthony A Scalzo; Cathy A Forbes; Andreas Suhrbier


Book ID
117433242
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
311 KB
Volume
17
Category
Article
ISSN
0264-410X

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✍ Marianne K. Gjertsen; Jens BjΓΈrheim; Ingvil Saeterdal; June Myklebust; Gustav Ga πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 119 KB πŸ‘ 1 views

Mutant p21-ras proteins contain sequences that distinguish them from normal ras, and represent unique epitopes for T-cell recognition of antigen-bearing tumour cells. Here, we examined the capacity of CD4 Ψ‰ and CD8 Ψ‰ T cells, generated simultaneously by mutant-ras-peptide vaccination of a pancreatic