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Pepsin inhibition by a high specific activity radioiodinated derivative of pepstatin

✍ Scribed by Robert Jay Workman; Donna W. Burkitt

Book ID
115704210
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
779 KB
Volume
194
Category
Article
ISSN
0003-9861

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High specific activity tritium labeling
High specific activity tritium labeling of vitamin D derivative RO275646
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The octahydroindenone intermediate was tritium labeled using T 2 O isotope exchange labeling, and then elaborated to the vitamin D derivative RO275646. Though this method of labeling was expected to give the minor isomer, it was the shortest and most convenient route to the high specific activity me