## Abstract ## Objectives/Hypothesis: To investigate whether the pepsin immunohistochemical (IHC) staining of the laryngeal mucosa epithelia is an available test for diagnosing laryngopharyngeal reflux (LPR) in clinic. ## Study Design: Prospective case series. ## Methods: Biopsy specimens from
β¦ LIBER β¦
Pepsin detection in patients with laryngopharyngeal reflux before and after fundoplication
β Scribed by Eelco Wassenaar; Nikki Johnston; Albert Merati; Martin Montenovo; Rebecca Petersen; Roger Tatum; Carlos Pellegrini; Brant Oelschlager
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 180 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0930-2794
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## Abstract ## BACKGROUND An association between laryngopharyngeal reflux (LPR) and laryngeal carcinoma has been suggested, but remains unproven. The current pilot study was performed to determine the incidence of LPR among patients with early laryngeal carcinomas or dysplasia and to examine the a