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Pentamidine reduces hERG expression to prolong the QT interval

✍ Scribed by Jason S Cordes; Zhuoqian Sun; David B Lloyd; Jenifer A Bradley; Alan C Opsahl; Mark W Tengowski; Xian Chen; Jun Zhou


Book ID
110008654
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
376 KB
Volume
145
Category
Article
ISSN
0007-1188

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Terodiline causes polymorphic ventricula
✍ D. A. Stewart; J. Taylor; S. Ghosh; G. J. A. Macphee; I. Abdullah; J. M. McLenac πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 453 KB

Recent reports have suggested an association between terodiline hydrochloride and cardiac arrhythmias. We report 4 patients presenting over a six month period who developed polymorphic ventricular tachycardia (polymorphic VT) while receiving treatment with this agent. In each case there was prolonga