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Pentafluorophenyl esters for the temporary protection of the ?-carboxy group in solid phase glycopeptide synthesis

โœ Scribed by Meldal, Morten; Jensen, Knud J.


Book ID
120009058
Publisher
The Royal Society of Chemistry
Year
1990
Tongue
English
Weight
318 KB
Volume
6
Category
Article
ISSN
0022-4936

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๐Ÿ“œ SIMILAR VOLUMES


Pentafluorophenyl esters for temporary c
โœ Morten Meldal; Klaus Book ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 251 KB

The compound A~GlcNACgl-NH-Fmoc (3) was eynthesixed and transformed into the &gluwsyl amine (1) which was subsequently acylated with Fmoc-Asp(CI)-Gpfp (5) prepared from the readily available Fmoc-Asp@-tBu)-G-pfp (4). The resulting Fmoc-Asn(A~GlcNAcfil-N-)-O-Pfp (6) was used as a buildiug block in th