Tumor-induced osteomalacia originating f
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Kenya Kobayashi; Kazunari Nakao; Kensuke Kawai; Ken Ito; Seiji Hukumoto; Takahir
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Article
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2010
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John Wiley and Sons
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English
⚖ 270 KB
👁 1 views
Background. Tumor-induced osteomalacia (TIO) is a rare clinical entity in which secondary osteomalacia is induced by tumor-related products. Fibroblast growth factor 23 (FGF-23) mRNA is overexpressed in the tumor tissue, leading to impaired reabsorption of phosphorus in the renal tubules and hypopho