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Penicillin Sulfones

โœ Scribed by Johnson, D. A.; Panetta, C. A.; Cooper, D. E.


Book ID
126133533
Publisher
American Chemical Society
Year
1963
Tongue
English
Weight
278 KB
Volume
28
Category
Article
ISSN
0022-3263

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In order to evaluate the importance of a hydrogen-bond donating substituent in the design of b-lactamase inhibitors, a series of C6-substituted penicillin sulfones, lacking a C2 0 substituent, and having an sp 3 hybridized C6, was prepared and evaluated against a representative classes A and C b-lac