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Penicillin imino chlorides III. A novel tricyclic β-lactam derived from the reaction of phenyl-5-indanyloxycarbonylketene with the imino chloride of penicillin v methyl ester

✍ Scribed by R.D Carroll; Larry L. Reed


Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
245 KB
Volume
16
Category
Article
ISSN
0040-4039

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✦ Synopsis


In a previous communication' we described base-catalyzed rearrangement of the imino chloride 1 of penicillin V methyl ester to oxazole 9. In the work described herein we report formation of novel B-lactam 8 which arises, after a complicated series of steps, from the interaction of 1 with ketene 3.