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Penetration without cells: Membrane translocation of cell-penetrating peptides in the model giant plasma membrane vesicles

✍ Scribed by Pille Säälik; Aira Niinep; Janely Pae; Mats Hansen; Dmitri Lubenets; Ülo Langel; Margus Pooga


Book ID
113694628
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
834 KB
Volume
153
Category
Article
ISSN
0168-3659

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## Abstract Cell penetrating peptides (CPPs) have been successfully used to mediate the intracellular delivery of a wide variety of molecules of pharmacological interest both __in vitro__ and __in vivo__, although the mechanisms by which the cellular uptake occurs remain unclear and controversial.