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Penetration of teniposide (VM-26) into human intracerebral tumors

โœ Scribed by David J Stewart; Michael T Richard; Herman Hugenholtz; Jean Dennery; Dev Nundy; Judith Prior; Vital Montpetit; Harry S Hopkins


Publisher
Springer US
Year
1984
Tongue
English
Weight
620 KB
Volume
2
Category
Article
ISSN
0167-594X

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Penetration of VP-16 (etoposide) into hu
โœ David J Stewart; Michael T Richard; Herman Hugenholtz; Jean M Dennery; Raymond B ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer US ๐ŸŒ English โš– 456 KB

VP-16 100 mg/m2 was given intravenously to 10 patients undergoing surgical resection of intracerebral tumors, and the drug was assayed in resected tumor using high pressure liquid chromatography. VP-16 concentrations varied from undetectable (less than .1 microgram/g) to 5.9 micrograms/g (mean, 1.4