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Penetration of small molecules into proteins studied by quenching of phosphorescence and fluorescence

โœ Scribed by Calhoun, D. B.; Vanderkooi, J. M.; Englander, S. W.

Book ID
126188310
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
847 KB
Volume
22
Category
Article
ISSN
0006-2960

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๐Ÿ“œ SIMILAR VOLUMES

Protein fluorescence quenching by small
Protein fluorescence quenching by small molecules: Protein penetration versus solvent exposure
โœ Dorothy B. Calhoun; Jane M. Vanderkooi; Gary R. Holtom; S. Walter Englander ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 748 KB

Experiments were done to test the thesis that acrylamide and similar small molecules can penetrate into proteins on a nanosecond time scale. The approach taken was to measure the pattern of fluorescence quenching exhibited by quenching molecules differing in molecular character (size, polarity, char