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Penetration of phospholipid monolayers by opioid peptides and opiate drugs (agonists and antagonists)

✍ Scribed by N. Bourhim; M.S. Elkebbaj; Y. Gargouri; P. Giraud; J. van Rietschoten; C. Oliver; R. Verger


Book ID
108029867
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
864 KB
Volume
1
Category
Article
ISSN
0927-7765

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The discovery of the prototype ␦ opioid antagonists TIPP (H-Tyr-Tic-Phe-Phe-OH) and TIP (H-Tyr-Tic-Phe-OH) in 1992 was followed by extensive structure-activity relationship studies, leading to the development of analogues that are of interest as pharmacological tools or as potential therapeutic agen