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Pemetrexed + gemcitabine no plus in pancreatic cancer

Book ID
120853284
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2005
Weight
120 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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πŸ“œ SIMILAR VOLUMES

The pemetrexed/gemcitabine combination i
The pemetrexed/gemcitabine combination in pancreatic cancer
✍ Hedy Lee Kindler πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 89 KB

Gemcitabine has modest antitumor activity in advanced pancreatic cancer. New agents are clearly needed. Pemetrexed (ALIMTA) is a novel antifolate that inhibits thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase. Pemetrexed has shown in vitro activity agai