Role of ethanol-inducible cytochrome p-4
โ
Mikihiro Tsutsumi; Yoshiro Matsuda; Akira Takada
๐
Article
๐
1993
๐
John Wiley and Sons
๐
English
โ 786 KB
Cytochrome P-450 2E1 is a specific isozyme of cytochrome P-450 induced by ethanol. P-450 2E1 may also be the only enzyme that metabolizes N-nitrosodimethylamine at a very low concentration. Because N-nitrosodimethylamine is a procarcinogen, the possibility that induction of P-450 2El by alcohol abus