PEG-mediated catalyst-free expeditious synthesis of 2-substituted benzimidazoles and bis-benzimidazoles under solvent-less conditions

✍ Scribed by Chhanda Mukhopadhyay; Pradip Kumar Tapaswi

• Book ID: 104095741
• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 190 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.08.041

✦ Synopsis

A wide variety of 2-substituted benzimidazoles and bis-benzimidazoles were synthesized in high yields by PEG-mediated catalyst-free synthesis under solvent-less conditions. The products were directly recrystallized from hot methanol. The reaction occurred giving excellent yields with low as well as high molecular weight PEGs.