✦ LIBER ✦

PEG enhances viral clearance on ceramic hydroxyapatite

✍ Scribed by Mark A. Snyder; Paul Ng; Heather Mekosh; Pete Gagnon

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 80 KB
Volume: 32
Category: Article
ISSN: 1615-9306
DOI: 10.1002/jssc.200900156

No coin nor oath required. For personal study only.

✦ Synopsis

Viral clearance across ceramic hydroxyapatite (CHT TM ) was examined in two elution systems: sodium chloride and sodium chloride plus poly(ethylene glycol) (PEG). In both cases clearance of xenotropic murine leukemia virus was significant (3-4 log) while that of minute virus of mice varied between 1.7 and 2.7 log; in addition, the addition of PEG to the elution buffer enhanced viral clearance. The data are in agreement with the previous results and demonstrate that additional clearance can be obtained by adding PEG to a ceramic hydroxyapatite buffer system.

📜 SIMILAR VOLUMES

Enhanced bone morphogenetic protein-2 pe

Enhanced bone morphogenetic protein-2 performance on hydroxyapatite ceramic surfaces

✍ A. Schuessele; H. Mayr; J. Tessmar; A. Goepferich 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 500 KB

## Abstract The immobilization of biomolecules on biomaterial surfaces allows for the control of their localization and retention. In numerous studies, proteins have been simply adsorbed to enhance the biological performance of various materials __in vivo__. We investigated the potential of surface