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Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence

✍ Scribed by Eric O. Johnson; Li-Shiun Chen; Naomi Breslau; Dorothy Hatsukami; Tania Robbins; Nancy L. Saccone; Richard A. Grucza; Laura J. Bierut


Book ID
108599225
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
235 KB
Volume
105
Category
Article
ISSN
0965-2140

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## Abstract ## Objectives Catechol‐__O__‐methyltransferase (COMT) may be a risk modifying gene for Nicotine dependence (ND) rather than a direct susceptibility gene for this phenotype. Brain nicotinic cholinergic receptors modulate dopaminergic transmission, and several variants within the neighbo