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Pedigree-based quantitative genetic analysis of interindividual variation in circulating levels of IGFBP-3

✍ Scribed by Ia Pantsulaia; Svetlana Trofimov; Eugene Kobyliansky; Gregory Livshits


Publisher
Springer
Year
2002
Tongue
English
Weight
96 KB
Volume
20
Category
Article
ISSN
0914-8779

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## Abstract Insulin‐like growth factor‐I (IGF‐I) and its major binding protein IGFBP‐3 have been implicated in breast carcinogenesis. We examined the associations between genetic variants and circulating levels of IGF‐I and IGFBP‐3 with proliferative benign breast disease (BBD), a marker of increas