Aberrant methylation in pediatric myelod
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Daniel O. Vidal; ValΓ©ria A. PaixΓ£o; Mariana Brait; Elisabeth X. Souto; OtΓ‘via L.
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Article
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2007
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Elsevier Science
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English
β 212 KB
## Background: Aberrant methylation of gene promoter region is responsible for inappropriate gene silencing, and it has been associated to initiation and progression of cancer. aberrant promoter methylation is frequently observed in adult patients with myelodysplastic syndrome (mds), but in pediatr