Pediatric Liver Disease

✍ Scribed by Robert L. Peters (auth.), M. M. Fisher, C. C. Roy (eds.)

• Publisher: Springer US
• Year: 1983
• Tongue: English
• Leaves: 291
• Series: Hepatology 5
• Edition: 1
• Category: Library

✦ Synopsis

This was an important Symposium in a rapidly developing field of interest. It was designed to draw attention to areas which have been neglected in standard hepatology textbooks and to review areas of controversy. It was also meant to help bridge the communication gap between hepatologists'caring for children and adults as well as between some areas of clinical and basic research. The Symposium was a substantial success. Unfortunately two of the twenty participants did not deliver a manuscript. The result is a publication which is late and which is not as complete as it should be. For this lateness and incompleteness the editors apolo­ gize most sincerely--especially to those participants who delivered their manuscripts on time but even to those who delivered their manu­ scripts late. perhaps the most noteworthy feature of this publication is the fact that material presented in May 1980 is by no means out of date. Apart from the section on Viral Hepatitis, one of the most rapidly evolving fields of medicine, the context of the Symposium remains disturbingly current. The neglect continues, the controversies remain. We hope that this publication will help draw investigators into liver research, provide a useful point of reference for· those in the field and stand as a monument to editors past, present and future, who have chased, are chasing and will chase manuscripts in vain.

✦ Table of Contents

Front Matter....Pages i-ix
Early Development of the Liver: A Review....Pages 1-15
Developmental Aspects of the Hepatic Circulation....Pages 17-38
Discussion....Pages 39-42
Developmental Aspects of Bile Acid Metabolism and Hepatic Function....Pages 43-53
Hepatic Drug-Metabolizing Enzymes during Embryonic and Fetal Development....Pages 55-93
Discussion....Pages 95-95
A Clinical Approach to Cryptogenic Cholestasis of the Newborn....Pages 97-103
The Role of Bile Acids in Pediatric Cholestasis....Pages 105-118
Microfilament Dysfunction in Cholestasis: Possible Involvement in Familial Pediatric Cholestatic Syndromes....Pages 119-129
Discussion....Pages 130-130
Extrahepatic Biliary Atresia: Clinical Aspects....Pages 131-136
Pathology and Pathogenesis of Extrahepatic Biliary Atresia....Pages 137-145
The Surgery of Biliary Atresia: Current Investigations....Pages 147-156
Discussion....Pages 156-160
Viral Hepatitis Type A: Redefinition of Virologic, Clinical and Epidemiologic Features....Pages 161-173
Discussion....Pages 175-175
Viral Hepatitis, Type B....Pages 177-186
Hepatitis Non A Non B: A Newly Recognized Old Disease....Pages 187-206
Discussion....Pages 207-215
Hereditary Fructose Intolerance....Pages 217-221
Deficiency of Fumarylacetoacetase in the Acute Form of Hereditary Tyrosinemia with Reference to Prenatal Diagnosis....Pages 223-235
A Metabolic Basis for Treatment of Type I Glycogen Storage Disease....Pages 237-254
Discussion....Pages 255-259
Wilson’s Disease — Hepatolenticular Degeneration the Importance of Early Diagnosis....Pages 261-270
Alpha-1-Antitrypsin Deficiency....Pages 271-282
Discussion....Pages 283-285
Closing Comments....Pages 287-287
Back Matter....Pages 289-296

✦ Subjects

Internal Medicine