Pediatric Inflammatory Bowel Disease

✍ Scribed by Zhi Wei PhD, Steven Baldassano MD, PhD Candidate, Hakon Hakonarson MD, PhD (auth.), Petar Mamula, Jonathan E. Markowitz, Robert N. Baldassano (eds.)

• Publisher: Springer-Verlag New York
• Year: 2013
• Tongue: English
• Leaves: 573
• Edition: 2
• Category: Library

✦ Synopsis

Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use.

Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.

✦ Table of Contents

Front Matter....Pages i-xix
Front Matter....Pages 1-1
Genetics of Inflammatory Bowel Diseases....Pages 3-12
Gut Immunity and Inflammatory Bowel Disease....Pages 13-23
Cytokines and Inflammatory Bowel Disease....Pages 25-33
The Gut Microbiota and IBD....Pages 35-42
Front Matter....Pages 43-43
Epidemiology of Pediatric Inflammatory Bowel Disease....Pages 45-57
Early Onset Inflammatory Bowel Disease....Pages 59-63
The Natural History of Crohn Disease in Children....Pages 65-71
Natural History of Ulcerative Colitis in Children....Pages 73-77
Natural History of Indeterminate Colitis....Pages 79-86
Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease....Pages 87-93
Liver Disease in Pediatric Inflammatory Bowel Disease....Pages 95-107
Growth Impairment in Pediatric Inflammatory Bowel Disease....Pages 109-125
Inflammatory Bowel Diseases and Skeletal Health....Pages 127-136
Puberty and Pediatric-Onset Inflammatory Bowel Disease....Pages 137-145
Classification of Inflammatory Bowel Disease in Children....Pages 147-157
Front Matter....Pages 159-159
The History and Physical Exam....Pages 161-163
Differential Diagnosis of Inflammatory Bowel Disease....Pages 165-174
Laboratory Evaluation of Inflammatory Bowel Disease....Pages 175-187
Radiologic Evaluation of Pediatric Inflammatory Bowel Disease....Pages 189-202
Endoscopic Modalities in Pediatric Inflammatory Bowel Disease....Pages 203-221
Front Matter....Pages 159-159
The Pathology of Chronic Inflammatory Bowel Disease....Pages 223-239
Videocapsule Endoscopy in Inflammatory Bowel Disease....Pages 241-248
Bone Health in Pediatric Inflammatory Bowel Disease....Pages 249-262
Assessment of Growth and Nutritional Status in Children with Inflammatory Bowel Disease....Pages 263-271
Front Matter....Pages 273-273
Pharmacogenetics in IBD....Pages 275-279
5-Aminosalicylate Therapy....Pages 281-288
Antibiotic Therapy....Pages 289-294
Nutritional Management of Inflammatory Bowel Disease....Pages 295-312
Probiotic Therapy....Pages 313-323
Corticosteroids....Pages 325-329
6-Mercaptopurine Therapy....Pages 331-337
Methotrexate....Pages 339-343
Infliximab Therapy for Pediatric Crohn Disease and Ulcerative Colitis....Pages 345-355
Biologic Therapies....Pages 357-383
Medical Treatment of Perianal Crohn Disease Fistulae....Pages 385-397
Management of Fulminant Colitis....Pages 399-402
Front Matter....Pages 403-403
Surgical Management of Crohn Disease in Children....Pages 405-415
Surgical Treatment of Ulcerative Colitis....Pages 417-429
Pouchitis After Ileal Pouch-Anal Anastomosis....Pages 431-439
Enteral Feeding Devices and Ostomies....Pages 441-446
Front Matter....Pages 447-447
Clinical Indices for Pediatric Inflammatory Bowel Disease Research....Pages 449-465
Clinical Trials (Clinician Perspective)....Pages 467-472
Clinical Trials (Industry Perspective)....Pages 473-480
Front Matter....Pages 481-481
Psychological Aspects of IBD in Children and Adolescents....Pages 483-490
Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease....Pages 491-503
Irritable Bowel Syndrome and Functional Gastrointestinal Disorders in Pediatric Inflammatory Bowel Disease....Pages 505-514
Inflammatory Bowel Disease in Pregnancy....Pages 515-525
Immunizations in the Child with Inflammatory Bowel Disease....Pages 527-530
Malignant Tumors Arising in Inflammatory Bowel Disease....Pages 531-545
Quality Improvement in Inflammatory Bowel Disease....Pages 547-554
Advocacy for Pediatric Patients with Inflammatory Bowel Disease....Pages 555-564
Legislative Advocacy....Pages 565-570
Transition from Pediatric to Adult Care....Pages 571-577
Back Matter....Pages 579-591

✦ Subjects

Gastroenterology