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Pediatric gastrointestinal stromal tumor in association with neuroblastoma

✍ Scribed by SHEELAH C. CHANGHO; J. ALLYSON NIECE; CAROL SAUNDERS; DOUGLAS C. RIVARD; ATIF AHMED

Book ID: 109344129
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 241 KB
Volume: 119
Category: Article
ISSN: 0365-5555
DOI: 10.1111/j.1600-0463.2010.02695.x

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## Abstract Somatic, activating mutations of __KIT__ or __PDGFRA__ are early oncogenic events in the majority of sporadic gastrointestinal stromal tumors (GISTs). Also a number of families with GISTs have been described in recent years. The familial GIST syndrome is a rare autosomal dominant disord