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Pd(PPh3)4/AgOAc-catalyzed one-pot synthesis of substituted 3,4-dihydronaphthalen-1(2H)-ones

✍ Scribed by Hui Liu, Peiyun Yan, Yan Li, Jinliang Liu, Qian Sun, Xingbin Wang, Cunde Wang


Book ID
113051498
Publisher
Springer Vienna
Year
2011
Tongue
English
Weight
530 KB
Volume
143
Category
Article
ISSN
0026-9247

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A series of 2,3-dihydroquinazolin-4(1H)-ones and quinazolin-4(3H)-ones have been synthesized in good to excellent yields and high selectivity by one-pot reaction using isatoic anhydride, ammonium acetate (or amines), and aldehydes in ethanol or in DMSO under mild conditions, respectively. The reacti