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PDK-1 Plays Essential Roles in the Regulation of Cell Size, Beta-adrenergic Response and Cell Survival in the Heart

✍ Scribed by Kaoru Ito; Hiroshi Akazawa; Masaji Tamagawa; Norio Suda; Wataru Ogawa; Masato Kasuga; Haruaki Nakaya; Issei Komuro


Book ID
119214223
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
57 KB
Volume
12
Category
Article
ISSN
1532-8414

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✍ Yoko Nagai-Tamai; Keiko Mizuno; Tomonori Hirose; Atsushi Suzuki; Shigeo Ohno πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 540 KB

## Abstract **Background:** Recent studies have revealed that aPKC (atypical protein kinase C), PAR‐3 and PAR‐6 play indispensable roles in the regulation of various cell polarization events, from worms to mammals, suggesting that they comprise an evolutionarily conserved protein machinery which is