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Pd(II)-Catalyzed Coupling Cyclization of 2,3-Allenoic Acids with Allylic Halides. An Efficient Methodology for the Synthesis of β-Allylic Butenolides

✍ Scribed by Ma, Shengming; Yu, Zhanqian


Book ID
126155092
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
92 KB
Volume
68
Category
Article
ISSN
0022-3263

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Efficient synthesis of 4-(2′-alkenyl)-2,
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4-(2%-Alkenyl)-2,5-dihydrofurans can be efficiently synthesized via the PdCl 2 -catalyzed coupling-cyclization of allylic halides with 2,3-allenols in DMA at rt in moderate to good yields. The regioselectivity is different from that of the Pd(0)-catalyzed coupling-cyclization of organic halides with

ChemInform Abstract: Efficient Synthesis
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