PDGF-C participates in branchial arch morphogenesis and is down-regulated by retinoic acid
โ Scribed by Jing Han; Li Li; Zhaofeng Zhang; Ying Xiao; Jiuxiang Lin; Yong Li
- Book ID
- 119379012
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 321 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0378-4274
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## Abstract **BACKGROUND:** Allโ__trans__โretinoic acid (RA) can produce branchial arch abnormalities in postimplantation rodent embryos cultured __in vitro__. Plateletโderived growth factor C (PDGFโC) was recently identified as a member of the PDGF ligand family. Many members of the PDGF family ar
We examined the mRNA expression of scleraxis, a non-myogenic helix-loop-helix type transcription factor in C2C12 myogenic cells. Scleraxis mRNA has been shown to be expressed in sclerotome and perichondrium of the embryos. We found that C2C12 cells express 1.2 kb scleraxis mRNA constitutively. Since