pDelayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests

Tolerance to cadmium hepatotoxicity by m

Tolerance to cadmium hepatotoxicity by metallothionein and zinc: in vivo and in vitro studies with MT-null mice

✍ Peter Coyle; Geralt Niezing; Tanya L. Shelton; Jeffrey C. Philcox; Allan M. Rofe 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 168 KB

The protective role of metallothionein (MT) in Cd-mediated hepatotoxicity was investigated in vivo and in vitro. Following injection of Cd (2 mg/kg, intraperitoneal or subcutaneous) hepatoxicity was significantly greater at 20 h in metallothionein-null (MT -/-) mice, compared with controls (MT+/+).