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PDE7A is expressed in human B-lymphocytes and is up-regulated by elevation of intracellular cAMP

✍ Scribed by Richard Lee; Sharon Wolda; Eunyi Moon; James Esselstyn; Carmen Hertel; Adam Lerner

Book ID
114283648
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
274 KB
Volume
14
Category
Article
ISSN
0898-6568

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## Abstract Langerhans cells (LC) act as potent antigen‐presenting cells (APC) for primary and secondary T cell‐dependent immune responses. LC express several costimulatory and/or adhesion molecules such as B7/BB1, which has been implicated as one of the important determinants for professional APC.