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PD18 - Filaggrin loss-of-function variants are associated with clinical reactivity to foods

✍ Scribed by Van Ginkel, Dorien; Koppelman, GH; Kollen, BJ; van der Heide, S; Kukler, J; Flokstra-de Blok, BMJ; Dubois, AEJ


Book ID
125404483
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
94 KB
Volume
4
Category
Article
ISSN
2045-7022

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Filaggrin loss-of-function variants are
✍ J. Van Limbergen; R.K. Russell; E.R. Nimmo; Y. Zhao; H. Liao; H.E. Drummond; G. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 100 KB

Background: Pediatric inflammatory bowel disease (IBD) has a high prevalence of coexistent atopy. Filaggrin (FLG) loss-of-function variants (null-alleles) are associated with eczema and asthma in association with eczema. The aim was to assess the contribution of FLG null-alleles to pediatric IBD sus