✦ LIBER ✦
Pd(0) promoted alkylation of enol phosphates with organoaluminium compounds and its synthetic applications
✍ Scribed by Mitsuyoshi Sato; Kazuhiko Takai; Koichiro Oshima; Hitosi Nozaki
- Book ID
- 104241585
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 222 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Keto carbonyl 1,2-and 1,3-transpositions with and without alkylation of the substrate are described together with ketone synthesis from thiocarboxylic S-ester.
Organoaluminium compounds react with enol phosphates to give alkylative coupling products in the presence of a catalytic amount of Pd(PPh3)4.1 The process provides a method of converting ketones into alkyl-substituted olefins regioselectively.