Pd(0)-Catalyzed Coupling−Cyclization of 2-(2‘,3‘-Allenyl)acetylacetates and Organic Halides: An Efficient Synthesis of 4,5-Dihydrofuran Derivatives
✍ Scribed by Ma, Shengming; Zheng, Zilong; Jiang, Xuefeng
- Book ID
- 120621497
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 163 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1523-7060
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4-(2%-Alkenyl)-2,5-dihydrofurans can be efficiently synthesized via the PdCl 2 -catalyzed coupling-cyclization of allylic halides with 2,3-allenols in DMA at rt in moderate to good yields. The regioselectivity is different from that of the Pd(0)-catalyzed coupling-cyclization of organic halides with