✦ LIBER ✦
Pd(0)-Catalyzed Bismetallative Cyclization of Enynes in the Presence of Bu3SnSiMe3 Using N-Heterocyclic Carbene as a Ligand
✍ Scribed by Yoshihiro Sato; Noriko Imakuni; Miwako Mori
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 104 KB
- Volume
- 345
- Category
- Article
- ISSN
- 1615-4150
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✦ Synopsis
Abstract
It was found that a nucleophilic N‐heterocyclic carbene could be utilized as a ligand for Pd(0)‐catalyzed bismetallative cyclization of enynes in the presence of Bu~3~SnSiMe~3~. An imidazolium salt having a bulky alkyl group attached to both nitrogen atoms of its imidazol‐2‐ylidene skeleton or an imidazolinium salt is suitable as a ligand precursor. The cyclized products obtained from this cyclization have both a vinylsilane moiety and a homoallylstannane moiety, whose utility in synthetic organic chemistry has been proven by transformation into cyclopropanol derivatives.