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PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

✍ Scribed by Marcus Mühlbauer; Martin Fleck; Christian Schütz; Thomas Weiss; Matthias Froh; Christian Blank; Jürgen Schölmerich; Claus Hellerbrand

Book ID
116651130
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
302 KB
Volume
45
Category
Article
ISSN
0168-8278

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## Abstract We have previously reported that interferon‐α (IFNα) induces apoptosis and EGF can antagonize this effect in human epidermoid cancer KB cells. Since apoptosis occurs together with cytoskeleton reorganization we have evaluated if IFNα and EGF could modulate cell remodeling in our experim