𝔖 Bobbio Scriptorium
✦   LIBER   ✦

PD-1 and Its Ligands in Tolerance and Immunity

✍ Scribed by Freeman, Gordon J.; Sharpe, Arlene H.; Keir, Mary E.; Butte, Manish J.

Book ID
111653737
Publisher
Annual Reviews
Year
2008
Tongue
English
Weight
461 KB
Volume
26
Category
Article
ISSN
0732-0582

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Programmed cell death 1 (PD-1) and its l
Programmed cell death 1 (PD-1) and its ligand PD-L1 are required for allograft tolerance
✍ Liqing Wang; Rongxiang Han; Wayne W. Hancock πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 429 KB

## Abstract Programmed cell death‐1 (PD‐1, CD279) and its widely expressed, inducible ligand, PD‐L1 (CD274), together dampen T cell activation, but whether they are essential for allograft tolerance is unknown. We show, using gene‐deficient mice and blocking mAbs in wild‐type mice, that costimulati

Macroautophagy in Immunity and Tolerance
Macroautophagy in Immunity and Tolerance
✍ Monique GannagΓ©; Christian MΓΌnz πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 143 KB
The negative costimulatory molecule PD-1
The negative costimulatory molecule PD-1 modulates the balance between immunity and tolerance via miR-21
✍ Dimitrios Iliopoulos; Melina Kavousanaki; Marianna Ioannou; Dimitrios Boumpas; P πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 339 KB

## Abstract Disruption of the programmed death‐1 (PD‐1) pathway leads to breakdown of peripheral tolerance and initiation of autoimmunity. The molecular pathways that mediate this effect remain largely unknown. We report here that PD‐1 knockout (PD‐1^βˆ’/βˆ’^) mice develop more severe and sustained Ag‐