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PCNA and p53

โœ Scribed by A. Mighell

Book ID
116169147
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
234 KB
Volume
31
Category
Article
ISSN
0964-1955

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The cyclin-dependent kinase inhibitor p21/WAF1 is regulated by p53-dependent and p53-independent pathways. In addition, p21/WAF1 binds with proliferating cell nuclear antigen (PCNA) and inhibits the action of PCNA. To investigate the possible role of p21/WAF1 in human hepatocellular carcinomas (HCCs