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PCN4 Decision-Analytic Model for the First-Line Therapy of Chronic Myeloid Leukemia

✍ Scribed by U. Rochau; G. Sroczynski; D. Wolf; S. Schmidt; A. Conrads-Frank; B. Jahn; K.R. Saverno; D. Brixner; G. Gastl; J. Radich; U. Siebert


Book ID
119312148
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
58 KB
Volume
15
Category
Article
ISSN
1098-3015

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First-line therapy for chronic myeloid l
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## Abstract The development of Bcr‐Abl tyrosine kinase inhibitors has dramatically changed the prognosis of patients with newly diagnosed chronic myeloid leukemia (CML). Standard‐dose imatinib (400 mg/day in chronic phase, 600 mg/day in advanced CML) now dominates the management of this disease, pr